Friday, June 4, 2010

Trichomoniasis; New findings from University of Alabama in the area of trichomoniasis described

c)Copyright 2010, AIDS Weekly via NewsRx.com

2010 MAY 17 - ( NewsRx.com) -- Current study results from the report, 'Treatment of trichomoniasis in pregnancy in sub-Saharan Africa does not appear to be associated with low birth weight or preterm birth,' have been published (see also Trichomoniasis). In this recent article published in the South African Medical Journal Suid-afrikaanse Tydskrif Vir Geneeskunde, scientists in the United States conducted a study "To determine whether treatment of trichomoniasis increases the risk of prematurity. Sub-analysis of a randomised trial."

"We analysed data from HPTN trial of antenatal and intrapartum antibiotics to reduce chorioamnionitis-related perinatal HIV transmission. Pregnant women from four sites in Africa. Gestational age at the time of delivery or mean birth weight. Of 2,428 women-infant pairs included, 428 (18%) had trichomoniasis at enrolment. There were no differences in infant age or birth weight between women with or without trichomoniasis. By randomisation group, there were no differences in gestational age at birth or birth weight. Of the 428 women diagnosed with trichomoniasis, 365 (83%) received antibiotics and 63 (15%) did not. In analysis of actual use of antibiotics, women with trichomoniasis who received no treatment were more likely to deliver a preterm infant when the symphysis-fundal height was used to estimate gestational age (36% v. 23%; p=0.03), but not when the Ballard score was used (16% v. 21%; p=0.41). There were no differences in mean birth weight between groups," wrote E. Stringer and colleagues, University of Alabama.

The researchers concluded: "In pregnant women in sub-Saharan Africa, most of whom were HIV-infected, neither trichomoniasis nor its treatment appears to influence the risk of preterm birth or a low-birth-weight infant."

Stringer and colleagues published their study in South African Medical Journal Suid-afrikaanse Tydskrif Vir Geneeskunde (Treatment of trichomoniasis in pregnancy in sub-Saharan Africa does not appear to be associated with low birth weight or preterm birth. South African Medical Journal Suid-afrikaanse Tydskrif Vir Geneeskunde, 2010;100(1):58-64).

Additional information can be obtained by contacting E. Stringer, University of Alabama at Birmingham, Dept. of Obstetrics and Gynecology, Birmingham, Alabama USA.

The publisher of the South African Medical Journal Suid-afrikaanse Tydskrif Vir Geneeskunde can be contacted at: Med Association S Africa, Med House Central Sq 7430 Pinelands Priv Bag X1, Johannesburg, South Africa.

Keywords: City:Birmingham, State:Alabama, Country:United States, Antibacterial, Antibiotics, Antimicrobial, HIV Infections, HIV/AIDS, Infectious Disease, Primate Lentiviruses, RNA Viruses, Retroviridae, Therapy, Treatment, Trichomonas Vaginitis, Trichomoniasis, Vertebrate Viruses, Viral Sexually Transmitted Diseases.

This article was prepared by AIDS Weekly editors from staff and other reports. Copyright 2010, AIDS Weekly via NewsRx.com.

Indexing (document details)

Author(s):Anonymous
Document types:Expanded Reporting
Publication title:AIDS Weekly. Atlanta: May 17, 2010. pg. 88
Source type:Periodical
ISSN:10691456
ProQuest document ID:2031280491
Text Word Count418
Document URL:http://proquest.umi.com/pqdweb?did=2031280491&sid=2&Fmt=3&clientId=45625&RQT=309&VName=PQD

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